In a collaboration between MatTek and Merck, HRV-challenged EpiAirway
recapitulated gene response profiles of human clinical HRV infection.
- EpiAirway's ciliated apical surface provides a more in-vivo-like environment to study respiratory infection.
- EpiAirway is readily infected with HRV.
- RNA-seq analysis identified 1485 genes significantly responsive to HRV infection in EpiAirway. These genes showed significant overlap with a previously reported in vivo dataset.