Technical References ( EpiOcular )
729. COSMETICS EUROPE MULTI-LABORATORY PRE-VALIDATION OF THE EPIOCULAR™ RECONSTITUTED HUMAN TISSUE TEST METHOD FOR THE PREDICTION OF EYE IRRITATION.
Pfannenbecker1, U., Bessou-Touya2, S., Faller3, C., Harbell4, J., Jacob5, T., Raabe6, H., Tailhardat7, M., Alépée8, N., De Smedt9, A., De Wever10, B., Jones11, P., Kaluzhny12, Y., Le Varlet13, B., McNamee14, P., Marrec-Fairley15, M., Van Goethem9, F. 1Beiersdorf AG, Hamburg, Germany. 2Laboratoire Pierre Fabre, Castres, France. 3Procter & Gamble/Cosmital, Marly, Switzerland. 4Mary Kay Inc., Dallas, TX, USA. 5Avon Products, Inc., Suffern, NY, USA. 6Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA. 7LVMH Recherche, St. Jean De Braye Cedex, France. 8L’Oréal Research & Innovation, Aulnay Sous Bois, France. 9Janssen Research & Development, Beerse, Belgium. 10Henkel AG & Co. KGaA, Düsseldorf, Germany. 11Safety and Environmental Assurance Centre, Unilever, Sharnbrook, UK. 12MatTek Corporation, Ashland, MA, USA. 13Consultant, Links Ingénierie, Paris, France. 14The Procter & Gamble Company, Egham, Surrey, UK. 15Colipa, Brussels, Belgium. Toxicology in Vitro, 27, 619–626, (2013).
706. PREDICTING EYE IRRITATION OF AGROCHEMICAL FORMULATIONS ACCORDING TO DIFFERENT CLASSIFICATION SCHEMES BY IN VITRO METHODS (BOVINE CORNEAL OPACITY AND PERMEABILITY AND EPIOCULAR EYE IRRITATION TEST).
Kolle1, S.N. Buechse2, A., Knieriem3, T., Mayer3, W., Rey Moreno1, M-C., van Cott4, A., van Ravenzwaay1, B., and Landsiedel1, R. 1BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany, 2BASF SE, Scientific Computing, Ludwigshafen, Germany, 3BASF SE, Agricultural Products – Formulation Development, Ludwigshafen, Germany, 4BASF Cooperation, Agricultural Products – Global Product Safety & Registration, Raleigh, NC, USA. EuroTox 2012.
688. UPDATE OF THE COLIPA EYE IRRITATION TASK FORCE STRATEGY AND PROGRAMME FOR DEVELOPMENT OF IN VITRO METHODS.
Alépée1, N., Bessou-Touya2, S., De Smedt3, A., De Wever4, B., Jones5, P., McNamee6, P., Marrec-Fairley7, M., Pfannenbecker8, U., Tailhardat9, M., Van Goethem3, F. 1L’Oréal, Aulnay Sous Bois Cedex, France, 2Laboratoire Pierre Fabre, Castres, France, 3Johnson & Johnson Pharmaceutical Research & Development, Beerse, Belgium, 4Henkel, Düsseldorf, Germany, 5Safety and Environmental Assurance Centre, Unilever, Sharnbrook, UK, 6The Procter & Gamble Company, Egham, Surrey, UK, 7Colipa, Brussels, Belgium, 8Beiersdorf, Hamburg, Germany, 9LVMH Recherche, France.
681. PROSPECTIVE VALIDATION STUDY OF RECONSTRUCTED HUMAN TISSUE MODELS FOR EYE IRRITATION TESTING.
McNamee1,2, P., Alépée3, N., Barroso4, J., Cole4, T., de Jong-Rubingh5, C., Eskes6, C., Freeman7, S.J., Kirmizidis4, G., Lammers8, J., Pfannenbecker9, U. and Zuang4, V. 1The Procter & Gamble Company, U.K.,2COLIPA, Belgium; 3L’Oréal, France; 4ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, Italy; 5TNO, The Netherlands; 6Services & Consultation on Alternative Methods (SeCAM), Agno, Switzerland; 7Farino Consulting, UK; 8TNO Triskelion, The Netherlands; 9Beiersdorf, Germany. Presented at 8th World Congress on Alternatives and Animal Use, Montreal, Canada, 2011.
673. IN-HOUSE VALIDATION OF THE EPIOCULAR™ EYE IRRITATION TEST AND ITS COMBINATION WITH THE BOVINE CORNEAL OPACITY AND PERMEABILITY TEST FOR THE ASSESSMENT OF OCULAR IRRITATION.
Kolle1, S.N., Kandárová2, H., Wareing1, B., van Ravenzwaay1, B., and Landsiedel1, R. 1BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany; 2MatTek In Vitro Life Science Laboratories, Bratislava, Slovakia. ATLA, 39, 365–387, (2011). ATLA, 39, 365–387, (2011).
653. DEVELOPMENT OF THE EPIOCULAR™ EYE IRRITATION TEST FOR HAZARD IDENTIFICATION AND LABELLING OF EYE IRRITATING CHEMICALS IN RESPONSE TO THE REQUIREMENTS OF THE EU COSMETICS DIRECTIVE AND REACH LEGISLATION.
Kaluzhny1, Y., Kandárová2, H., Hayden1, P., Kubilus1, J., d’Argembeau-Thornton1, L., and Klausner1, M. 1MatTek Corporation, Ashland, MA, USA; 2MatTek In Vitro Life Science Laboratories, Bratislava, Slovakia. ATLA, 39, 339-364, (2011).
615. COLGATE-PALMOLIVE'S PROGRAM TO VALIDATE THE EPIOCULAR™ HUMAN TISSUE CONSTRUCT MODEL.
Rios-Blanco, M., Blazka, M. Colgate-Palmolive. Presented by Colgate at Paris, June 2003.
579. IN VITRO APPROACHES FOR PREDICTING IRRITATION POTENTIAL OF TOPICAL EXPOSURES TO THE SKIN AND EYES.
Harbell, J.W. Mary Kay, Dallas, Texas.
534. USE OF HPLC/UPLC INSTEAD OF PHOTOMETRY FOR EVALUATION OF MTT IN IN VITRO IRRITATION ASSAYS BASED ON HUMAN RECONSTRUCTED TISSUE FOR ASSESSMENT OF COLOURED TEST MATERIALS.
Faller1, C., Sieber1, T., McNamee2, P.M., Pfuhler1, S., Goebel3, C. 1Procter & Gamble-Cosmital SA, Marly, Switzerland, 2Procter & Gamble Technical Centres Ltd, Egham, Surrey, U.K. 3Procter & Gamble Service GmbH, Darmstadt, Germany. VII World Congress on Alternatives and Animal Use in the Life Sciences, Rome, Italy. Sept. 1, 2009.
533. EYE AND SKIN IRRITATION IN 3-D HUMAN TISSUE CONSTRUCTS USING MTT AND ATP ENDPOINTS.
Raabe2, H., Burdick1, J., Hanlon2, E., Hilberer2, A., Hyder2, M., Inglis2, H., Kong2, A., Majewski1, S., McNamara1, M., Mun2, G., Nash2, J., Wilt2, N. 1Beauty Avenues, Reynoldsburg, OH, USA. 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA. VII World Congress on Alternatives & Animal Use in the life Sciences, Rome, Italy, Sept 1, 2009.
524. TESTING OF THE EPIOCULAR TISSUE MODEL FOLLOWING EXTENDED SHIPPING TIMES.
Klausner1, M., Genno2, M., Handa2, Y., Ichinose2, F., Hayden1, P., and Kubilus1, J. 1MatTek Corporation, Ashland, MA 01721. 2Kurabo Industries, Ltd., Osaka, Japan. Presented at Society of Toxicology Meeting (2009).
514. PREDICTION OF OCULAR IRRITATION POTENTIAL OF SURFACTANTS-BASED FORMULATIONS AT DIFFERENT CONCENTRATIONS USING THE EPIOCULAR MODEL.
Yin, X.J., Dang, A.H., Gill, A., Rodriguez, C., Pham, H., Armbrister, W., Harbell, J.W., and Jones, B.C. Mary Kay, Inc., Dallas, TX, USA. Poster presented at SOT (2009).
513. COLIPA PROGRAM ON OPTIMIZATION OF EXISTING IN VITRO EYE IRRITATION ASSAYS FOR ENTRY INTO FORMAL VALIDATION: TECHNOLOGY TRANSFER AND INTRA/INTER LABORATORY EVALUATION OF EPIOCULAR ASSAY FOR CHEMICALS.
Harbell1, J.W., Le Varlet2, B., Marrec-Fairley3, M., Kaluzhny4, Y., McNamee5, P. 1 1Mary Kay, Inc, Addison, TX, USA. 2Consultant, Ingénierie, Montélier, France. 3COLIPA, Brussels, Belgium. 4MatTek Corp., Ashland, MA, USA. 5The Procter & Gamble Co., Egham, United Kingdom. Poster #378, Society of Toxicology, (2009). The Toxicologist, 108, 1, 79 (2009).
506. THE UTILIZATION OF THE EPIOCULAR HUMAN TISSUE MODEL TO ASSESS AND COMPARE THE IRRITATION POTENTIAL OF MULTIPLE SURFACTANT SYSTEMS USED IN SHAMPOOS AND FACIAL CLEANSERS.
Vavilikolanu1, P., Lazaro1, C., Mun2, G., Hilberer2, A., Hyder2, M., Raabe2, H., and Curren2, R. 1Alberto-Culver Company, Melrose Park, IL, USA 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA. Presented at the 47th Annual Society of Toxicology Meeting Seattle, WA, (2008). The Toxicologist, 102, 1, 66 (2008).
457. EXPANDED UTIILZATION OF THE EPIOCULAR HUMAN TISSUE MODEL FOR OCULAR IRRITATION TESTING.
Kaluzhny, Y., Thornton, L., Hayden, P., Kandarova, H., and Klausner, M. MatTek Corporation, Ashland, MA, USA. The Toxicologist, 101(1), 66 (2008).
454. EXPERIENCES IN THE DEVELOPMENT AND UTILIZATION OF AN IN VITRO SAFETY TESTING PROGRAM FOR HAIR CONDITIONERS.
Vavilikolanu1, P., Lazaro1, C., Mun2, G., Hilberer2, A., Hyder2, M., Raabe2, H., and Curren2, R. 1Alberto-Culver Company, Melrose Park, IL, USA, 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA. Presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan August 21-25, (2007).
442. REGULATORY REQUIREMENTS FOR IN VITRO SYSTEMS TO MEET PERFORMANCE STANDARDS OVER TIME AS WELL AS DURING VALIDATION.
Klausner, M., Kubilus, J., Ayehunie, S., Hayden, P., Chua, G., Sheasgreen, J. MatTek Corporation, Ashland, MA 01721. Society of Toxicology 46th Annual Meeting, Charlotte, NC, Abstract 1524, (2007). The Toxicologist, 96, 1, 315 (2007).
436. USE OF THE EPIOCULAR ASSAY FOR PRECLINICAL QUALIFICATION OF FORMULAS FOR HUMAN CLINICAL STUDIES.
Niranjan, P., Dang, A.H., January, B.G., Gomez, C., Harbell, J.W. Mary Kay, Inc., Dallas, TX, USA. Society of Toxicology 46th Annual Meeting, Charlotte, NC, (2007). The Toxicologist, 96, 1, 249 (2007).
402. DEVELOPMENT OF IMPROVED EPIOCULAR™ TEST PROTOCOLS FOR SCREENING OF SEVERE OCULAR IRRITANTS.
Jackson, G.R. Jr., Hayden, P.J., Kubilus, J., Kaluzhny, Y., Klausner, M. MatTek Corporation, Ashland, MA, USA. Presented at the 45th Society of Toxicology Meeting, San Diego CA, March 5-9, (2006). The Toxicologist, 90, 1, 326 (2006).
392. USE OF HUMAN SKIN EQUIVALENT CULTURES FOR COSMETIC BENEFIT SCREENING.
McPhail1, S., Messersmith1, E., Thomas1, R., Mullins1, L., Osborne1, R., Grove2, G. 1Procter and Gamble, Miami Valley Innovation Center, Beauty Technology Division, 11810 East Miami River Road Cincinnati, OH 45252. 2CyberDERM, 700 Parkway, Broomall, PA 19008. Presented at the American Academy of Dermatology, New Orleans, LA, February 19, (2005).
377. PROGRAM TO REDUCE ANIMAL TESTING FOR EPA REGISTRATIONS OF ANTIMICROBIAL PRODUCTS.
Sauers1, L., Acuff1, K., Marsman1, D., Vedula2, U., Cuellar2, N., Curren3, R., Harbell3, J., Quinn4, P. 1The Proctor & Gamble Co., Cincinnati, Ohio, USA; 2S.C. Johnson, Racine, Wisconsin, USA; 3Institute for In Vitro Sciences, Gaithersburg, Maryland, USA; 4The Accord Group, Washington, DC, USA.
374. IN VITRO METHODS FOR ASSESSING OCULAR IRRITANCY OF COSMETICS.
Richert, S., Schrader, A., Schrader, K. Institute Dr. Schrader Creachem GmbH, Holzminden, Germany. Presented at 5th World Congress, Berlin, Germany, August 21-25, (2005).
371. IN VITRO SKIN EQUIVALENT MODELS FOR TOXICITY TESTING.
Hayden, P.J., Ayehunie, S., Jackson, G.R., Kupfer-Lamore, S., Last, T.J., Klausner, M., Kubilus, J. MatTek Corporation, Ashland, MA, U.S.A. Published in Alternative Toxicological Methods. Editors H. Salem, S.A. Katz. CRC Press LLC, Boca Raton, FL, USA, 229-247 (2003).
356. EPIOCULAR HUMAN CELL CONSTRUCT: TISSUE VIABILITY AND HISTOLOGICAL CHANGES FOLLOWING EXPOSURE TO SURFACTANTS.
Blazka1, M., Diaco2, M., Harbell2, J., Raabe2, H., Sizemore2, A., Wilt2, N., Bagley1, D. 1Colgate-Palmolive Co., Piscataway, NJ, USA; 2Institute for In Vitro Sciences, Inc., Gaithersburg, MD, USA. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2001, 409, (2005).
354. HIGH-THROUGHPUT IN VITRO MODELS OF HUMAN EPIDERMIS AND OCULAR EPITHELIUM FOR PRECLINICAL SAFETY AND EFFICACY TESTING OF CONSUMER PRODUCTS AND PHARMACEUTICALS.
Jackson, G., Kubilus, J., Klausner, M., Sheasgreen, J., Hayden, P. MatTek Corporation, Ashland, MA. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2003, 409-410, (2005).
353. LONG TERM REPRODUCIBILITY OF EPIOCULAR™, A THREE-DIMENSIONAL TISSUE CULTURE MODEL OF THE HUMAN CORNEAL EPITHELIUM.
Klausner, M., Sheasgreen, J., Kubilus, J., Hayden, P. MatTek Corporation, Ashland, MA. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 6-10, 2005. The Toxicologist, 84, (1), Abstract # 2002, 409, (2005).
348. COMPARATIVE ASSESSMENT OF TWO EYE AREA COSMETIC FORMULATIONS THROUGH EVALUATION OF ALTERNATIVE EYE IRRITATION METHODS RELATIVE TO ENDPOINTS MEASURED IN A HUMAN CLINICAL SUB-ACUTE STUDY DESIGN.
Burdick2, J.D., Gao3, Y., Kanengiser3, B., Merrill1, J.C., Harbell1, J.W. 1Institute for In Vitro Sciences, Inc., Gaithersburg, MD; 2Bath & Body Works, Reynoldsburg, OH; 3Clinical Research Laboratories, Inc., Piscataway, NJ. Presented at Society of Toxicology Annual Meeting, Salt Lake City, Utah, March 9-13, (2003). The Toxicologist, 72, S1, 220 (2003).
333. DI-PPG-2-MYRETH-10 ADIPATE REDUCES IRRITATION AND INFLAMMATION CAUSED BY COSMETIC PRODUCTS.
Joseph¹, L.B., DeShields², L., Pereira¹, A.G., Stoudemayer, M.J., Langley¹, N.A. ¹Croda Inc., Edison, NJ 08837, ²S.K.I.N. Inc., Conshohocken, PA 19428. J. Invest. Dermatol., 122, (3), A7, Abstract #40, (2004).
299. ASSESSMENT OF HUMAN SKIN IRRITATION: VALIDATION OF IN VITRO MODELS.
MatTek Scientific, Marketing Staff. MatTek Corporation, Ashland, MA (USA). May 2003.
285. EVALUATING THE OCULAR IRRITATION POTENTIAL OF 54 TEST ARTICLES USING THE EPIOCULAR™ HUMAN TISSUE CONSTRUCT MODEL (OCL-200).
ME Blazka1, JW Harbell2, M Klausner3, J Merrill2, J Kubilus3, C Kloos1 and DM Bagley1. 1Colgate-Palmolive Co., Piscataway, NJ, USA. 2Institute for In Vitro Sciences, Gaithersburg, MD, USA. 3MatTek Corp., Ashland, MA, USA. The Toxicologist, 72, S1, 221 (2003).
259. ASSESSMENT OF OCULAR IRRITATION RANGES OF MARKET-LEADING COSMETIC AND PERSONAL-CARE PRODUCTS USING AN IN VITRO TISSUE EQUIVALENT.
McCain, N.E., Binetti, R.R., Gettings, S.D., Jones, B.C. Cell Biology & In Vitro Toxicology, Avon Products, Inc., Suffern, NY. The Toxicologist, 66 (1-S), 243, Soc. of Toxicol. (Reston, VA), Abstract #1191, (2002).
253. THE EFFECTS OF KNOWN EYE IRRITANTS ON THE SKINETHIC™ AND EPIOCULAR™ MODELS OF CORNEAL EPITHELIUM.
Jones, P., King, A. and Fentem, J. Safety and Environmental Assurance Centre., Unilever Colworth Laboratory, Colworth House, Sharnbrook, Bedford, MK44 1LQ, UK. Presented at the 43rd International Conference of the European Tissue Culture Society, Granada, Spain, September 30-October 3, (2001).
248. COMPARATIVE EVALUATION OF FIVE IN VITRO TESTS FOR ASSESSING THE EYE IRRITATION POTENTIAL OF HAIR-CARE PRODUCTS.
Jones1, P.A., Budynsky2, E., Cooper1, K.J., Decker2, D., Griffiths1, H.A., and Fentem1, J.H. 1Safety & Environmental Assurance Centre (SEAC), Unilever Colworth Laboratory, Sharnbrook, Bedfordshire MK44 1LQ, UK; 2Unilever Home & Personal Care, 3100 Golf Road, Rolling Meadows, IL 60008, USA. ATLA 29, 669-692, (2001).
223. HUMANE ENDPOINTS AND ACUTE TOXICITY TESTING.
Sass, N. Alabama Department of Public Health, Montgomery, Alabama, USA. ILAR Journal, 41(2), 14-23, (2000).
191. THE EPIOCULAR TISSUE MODEL: IN VIVO VERSUS IN VITRO DRAIZE SCORES FOR CONSUMER PRODUCTS.
Klausner1, M., Osborn1, M., Bellavance1, K., Breyfogle1, B., Kubilus1, J., Cerven2, D.R., DeGeorge2, G. 1MatTek Corp., Ashland, MA, 2MB Research Laboratories, Spinnerstown, PA Toxicological Sciences, 54, (1), 188 Abstr. #884 (2000).
190. COLGATE-PALMOLIVE'S PROGRAM - VALIDATE THE EPlOCULAR HUMAN TISSUE CONSTRUCT MODEL (OCL-200).
Blazka1, M.E., Harbell2, J.W., Klausner3, M., Raabe2, H., Kubilus3, J., Hsia4, F., Minerath5, B., Bagley1, D.M. 1Colgate-Palmolive Co., Piscataway NJ, 2Institute for In Vitro Sciences, Gaithersburg, MD, 3MatTek Corp., Ashland, MA, 43M Co., St. Paul, MN, 5Kimberly Clark, Neenah, WI. Toxicological Sciences, 54, (1), 188, Abstr. #884 (2000).
183. THE APPLICATION OF REFERENCE STANDARDS IN THE PREVALIDATION AND VALIDATION OF IN VITRO TESTS FOR EYE IRRITATION.
Brantom, P., Fentem1, J., Balls2, M., Cassidy3, S. BIBRA International, Woodmansterne Road, Carshalton, Surrey SM5 4DS, UK, 1SEAC Toxicology, Unilever Research, Colworth, Sharnbrook, Bedfordshire MK44 1LQ, UK, 2ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, 21020 Ispra (Va) Italy, 3Dow Corning, Rue General de Gaulle 62, 1310 la Hulpe, Belgium. ATLA, 27, 332, (1999).
178. COLGATE-PALMOLIVE'S PROGRAMME TO VALIDATE THE EPIOCULAR HUMAN TISSUE CONSTRUCT MODEL (OCL-200).
Blazka, M.E., Harbell1, J.W., Klausner2, M., Raabe1, H., Kubilus2, J., Hsia3, F., Minerath4, B., Bagley, D.M. Colgate-Palmolive, Piscataway, NJ, USA, 1Institute for In Vitro Sciences, Gaithersburg, MD, USA, 2MatTek, Corp. Ashland, MA, USA, 33M, St Paul, MN, USA, 4Kimberly Clark, Neenah, WI, USA. ATLA, 27, 331, (1999).
176. THE EPIOCULAR PREDICTION MODEL: A REPRODUCIBLE IN VITRO MEANS OF ASSESSING OCULAR IRRITANCY POTENTIAL.
Klausner1, M., Sheasgreen1, J., Breyfogle1, B., Sennott1, H., Liebsch2, M., Kubilus1, J. 1MatTek Corp., Ashland, MA 01721, USA, 2ZEBET, 12277 Berlin, Germany. ATLA, 27, (special issue), 299, (1999). Published in Alternative Toxicological Methods. Editors H. Salem, S.A. Katz. CRC Press LLC, Boca Raton, FL, USA, 229-247 (2003).
167. THE EPIOCULAR PREDICTION MODEL - A REPRODUCIBLE IN VITRO MEANS OF ASSESSING OCULAR IRRITANCY POTENTIAL.
Klausner, M., Sennott, H.A., Breyfogle, B., Makwana, A., Kubilus, J. MatTek Corp., Ashland, MA, USA. The Toxicologist, 48 (1-S), 336, Soc. of Toxicology (Reston, VA), Abstract #1583, (1999).
166. FURTHER EVALUATION OF THE EPIDERM AND EPIOCULAR IN VITRO IRRITATION MODELS.
Nicastro, S.C., Ladics, G.S. The DuPont Co., Haskell Laboratory for ToxicoIogy and Industrial Medicine, Newark, DE. SOT 1999 Annual Meeting. The Toxicologist, 48 (1-S), 70, Soc. of Toxicology (Reston, VA), Abstract #360, (1999).
159. THE EYE IRRITATION TESTING OF THE ORGANIC SOLVENTS ON IN VITRO TEST USING 3-D CORNEAL MODEL.
Akaza, N., Kojima, H., Katada. T., Konishi, H. Research Institute, Nippon Menard Cosmetic Co., Ltd. Presented at 12th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments, Sendai, Japan, November 18-19, (1998).
151. MATTEK'S TISSUE MODELS: NEW DEVELOPMENTS.
Klausner, M. MatTek Corp., Ashland, MA 01721. Presented at International Business Conference, "Latest In Vitro Testing Methods for Skin Care, Cosmetics, and Household Products," Washington, D.C., (1997).
147. THE EPIOCULAR PREDICTION MODEL: AN ACCURATE, REPRODUCIBLE IN VITRO MEANS OF ASSESSING OCULAR IRRITANCY POTENTIAL.
Klausner, M., Sennott, H.A., Breyfogle, B., Makwana, A., Kubilus, J. MatTek Corp., Ashland, MA. Toxicology In Vitro, 12, (4), 455-461 (1998).
146. EVALUATION OF THE EPIOCULAR TISSUE MODEL AS AN ALTERNATIVE TO THE DRAIZE EYE IRRITATION TEST.
1Stern, M., 2Klausner, M., 1Alvarado, R., 1Renskers, K., 1Dickens, M. 1Avon Products, Inc., Suffern, NY, 2MatTek Corp., Ashland, MA. Toxicology In Vitro, 12, 455-461, (1998).
142. EPIOCULAR PREDICTION MODEL. A REPRODUCIBLE IN VITRO TISSUE CULTURE MEANS OF PREDICTING DRAIZE SCORES.
Kubilus, J., Sennott, H., Makwana, A., Klausner, M. MatTek Corp., Ashland, MA. The Toxicologist, 36 (1), 44, Soc. of Toxicol. (Reston, VA), Abstract #222, (1997).
141. DEMONSTRATING THE OCULAR SAFETY OF AN EYE COSMETIC PRODUCT USING ALTERNATIVES TO ANIMAL EYE IRRITATION TESTS.
Ghassemi1, A., Osborne1, R., Kohrman1, K. A., Roddy1, M. T., Harbell2, J.W., Kanengiser3, B.E. 1The Procter & Gamble Company, Hunt Valley, MD and Cincinnati, OH, 2Microbiological Associates, Inc. Rockville, MD, 3Clinical Research Laboratories, Inc., Piscataway, NJ. Sponsored by L.D. Lehman-McKeeman. The Toxicologist, 36 (1), 42, Soc. of Toxicol. (Reston, VA), Abstract #221, (1997).
139. PREDICTION OF OCULAR IRRITATION POTENTIAL OF AIR CARE PRODUCTS USING IN VITRO TOPICAL APPLICATION ASSAYS.
Manderfield1, C.E., Swanson1, J.E., Kennedy1, O., Lee2, M.K., Bauernschub2, M.A., Harbell2, J.W. 1S. C. Johnson & Son, Inc., Racine, WI, 2Microbiological Associates, Inc., Rockville, MD. Sponsored by R. D. Curren. The Toxicologist, 36 (1), 44, Soc. of Toxicol. (Reston, VA), Abstract #223, (1997).
135. REPRODUCIBILITY AND CORRELATION OF EPIOCULAR, A THREE-DIMENSIONAL TISSUE CULTURE MODEL OF HUMAN CORNEAL EPITHELIUM.
Sheasgreen, J., Kubilus, J., Sennott, H., Ogle, P., Klausner, M. MatTek Corp., Ashland, MA. ATLA, 24, Special Issue, 284, Abstract #284, (1996).
130. A COMPARISON OF IN VITRO EYE IRRITATION TEST DATA FOR ORGANOSILICON COMPOUNDS.
Cassidy, S. L., Stanton, E. Dow Corning Toxicology Laboratory, Midland, MI, USA. Society of Toxicology Annual Meeting, Anaheim, CA. The Toxicologist, 30 (1), 123, Soc. of Toxicol. (Reston, VA), Abstract # 629, (1996).
129. REPRODUCIBILITY AND CORRELATION OF EPIOCULAR™, A THREE-DIMENSIONAL TISSUE CULTURE MODEL OF THE HUMAN CORNEAL EPITHELIUM.
Sheasgreen, J., Kubilus, J., Sennott, H., Ogle, P., Klausner, M. MatTek Corp., Ashland, MA. The Toxicologist, 30 (1), 128, Soc. of Toxicol. (Reston, VA), Abstract# 653, (1996).
115. INITIAL CHARACTERIZATION OF A NEW MODEL FOR OCULAR IRRITANCY TESTING.
Ricker, H.A., Neal, P.J., Kubilus, J., Klausner, M. MatTek Corp., Ashland, MA. In Vitro Cell & Devel. Biol., 30A(3), Abstract #T-1004, June (1994).
