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(References) EpiDermFT (EFT-400)
 

 
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Technical References

EpiDermFTTM Tissue Model

 

 

730. METABOLICALLY COMPETENT HUMAN SKIN MODELS: ACTIVATION AND GENOTOXICITY OF BENZO[A]PYRENE.

Brinkmann1, J., Stolpmann1, K., Trappe1, S., Otter1, T., Genkinger1, D., Bock2, U., Liebsch3, M., Henkler1, F., Hutzler1, C., and Luch1,3, A. 1German Federal Institute for Risk Assessment (BfR), Department of Product Safety, 10589 Berlin, Germany; 2Across Barriers GmbH, 66123 Saarbrücken, Germany; and 3German Federal Institute for Risk Assessment (BfR), Department of Experimental Toxicology and Center for Alternatives to Animal Testing, 12277 Berlin, Germany. Toxicological Sciences, 131(2), 351–359 2013.

 

727. NOVEL SILK FIBROIN/ELASTIN WOUND DRESSINGS.

Vasconcelos1, A., Gomes2, A.C., Cavaco-Paulo1, A. 1Universidade do Minho, Departamento de Engenharia Têxtil, Campus de Azurém, 4800-058 Guimarães, Portugal, 2Centre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, 4710-057 Braga, Portugal. Acta Biomaterialia, 8, 3049–3060, (2012).

 

726. CELL TYPE-DEPENDENT GENE TRANSCRIPTION PROFILE IN A THREE-DIMENSIONAL HUMAN SKIN TISSUE MODEL EXPOSED TO LOW DOSES OF IONIZING RADIATION: IMPLICATIONS FOR MEDICAL EXPOSURES.

von Neubeck1,  C., Shankaran2, H., Karin1,N.J., Kauer1, P.M., Chrisler1, W.B.,  Wang1, X., Robinson1, R.J., Waters2, K.M., Tilton2, S.C. and Sowa1, M.B.   1Department of Systems Toxicology, Pacific Northwest National Laboratory, Richland, Washington,  2Department of Computational Biology and Bioinformatics, Pacific Northwest National Laboratory, Richland, Washington.  Environ. Mol. Mutagen, 53, 247–259, (2012).

 

723. BIOCHEMICAL INVESTIGATION AND GENE ANALYSIS OF EQUOL: A PLANT AND SOY-DERIVED ISOFLAVONOID WITH ANTIAGING AND ANTIOXIDANT PROPERTIES WITH POTENTIAL HUMAN SKIN APPLICATIONS.

Gopaul1, R., Knaggs1, H.E. and Lepha2, E.D.  1Nu Skin Enterprises, Personal Care Products Division, Provo, Utah, USA. 2Department of Physiology and Developmental Biology and The Neuroscience Center, Brigham Young University, Provo, Utah, USA. Intl. U. of Biochem. and Molec. Biology, Inc., 38, (1), 44-52, (2012).

 

722. QUANTITATIVE PHOSPHOPROTEOMICS IDENTIFIES FILAGGRIN AND OTHER TARGETS OF IONIZING RADIATION IN A HUMAN SKIN MODEL.

Yang, F., Waters, K.M., Webb-Robertson, B-J, Sowa, M.B., von Neubeck, C., Aldrich, J.T., Markillie, L.M., Wirgau, R.M., Gritsenko, M.A.,  Zhao, R., Camp II, D.G., Smith, R.D. and Stenoien, D.L. Pacific Northwest National Laboratory, Richland, WA, USA.  Experimental Derm.,  21, 352-357, (2012).

 

705. γ-H2AX FORMATION IN THREE-DIMENSIONAL HUMAN SKIN AND CELL MODELS FOLLOWING INVITRO EXPOSURE TO SULFUR MUSTARD.

Miller, A., Waraich, N., Clark, O., Nealley, E., Leiter, K. and Smith, W. Research Division, US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland. Society of Toxicoloy Meeting, March 2009.

 

691. CONFOCAL MICROSCOPY FOR MODELING ELECTRON MICROBEAM IRRADIATION OF SKIN.

Miller1, J.H., Chrisler2, W. B., Wang3, X., Sowa2, M.B. 1School of Electrical Engineering and Computer Science, Washington State University Tri-Cities, Richland, WA 99354, USA. 2Cell Biology and Biochemistry, Pacific Northwest National Laboratory, Richland, WA 99354, USA. 3Biological Monitoring and Modeling, Pacific Northwest National Laboratory, Richland, WA 99354, USA. Radiat Environ Biophys,  50:365–369 (2011).

 

669. EVALUATION OF ANTI-INFLAMMATORY AND ATROPHOGENIC EFFECTS OF GLUCOCORTICOIDS ON RECONSTRUCTED HUMAN SKIN.

Weindl, G., Castello, F., and Schäfer-Korting, M.  Institut für Pharmazie (Pharmakologie und Toxikologie), Freie Universität Berlin, Berlin, Germany. ATLA, 39, 173-187, 2011.

 

658. EVALUATION OF XENOBIOTIC METABOLISM IN HUMAN RECONSTRUCTED SKIN MODELS FOR GENOTOXICITY TESTING.

Jackh1, C, Blatz1, V., Fabian1, E., Reisinger2 , K., van Ravenzwaay1 , B., Trappe3, S., Landsiedel1, R.  1Experimental Toxicology and Ecology, BASF SE, 67056 Ludwigshafen, Germany. 2Henkel AG & CO. KGaA, 40191 Düsseldorf, Germany.  3Federal Institute for Risk Assessment (BfR), 14195 Berlin, Germany. Presented at SOT 2011, Abstract #1005.

 

654. ORGANOTYPIC IN VITRO HUMAN EPITHELIAL MODELS WITH ENGINEERED TOXICOLOGIC REPORTER FUNCTIONS.

Hayden, P.J.,  Jackson, G.R., Stolper, G., Armento, A., Bolmarcich, J., Kandarova, H., and Klausner, M. MatTek Corporation, Ashland, MA, USA. Presented at SOT 2011, Abstract #2839

 

652. USE OF EPIDERM FULL THICKNESS(EFT) SKIN CULTURES AS AN IN VITRO MODEL FOR WOUND HEALING.

Hayden2,, P., Sachdeva1, M., Shah1, P.P., Desai1, U.S., Patlolla1, R., Klausner2, M. 1Pharmacy, Florida A&M University, Tallahassee, FL. USA. 2MatTek Corporation. Ashland. MA. USA. Presented at SOT 2011, Abstract #2556.

 

651. TIMECOURSE OF HEALING AFTER UV-INDUCED DAMAGE IN THE EPIDERM-FT IN VITRO HUMAN SKIN MODEL.

Stolper, G., Cooney, C., Armento, A., Oldach, J.,  Letasiova, S.,  Klausner, M., and Hayden, P.J. MatTek Corporation, Ashland, MA, USA. Presented at SOT 2011, Abstract #2575.

 

650. PARP-1 ACTIVITY IS INVOLVED IN THE SOLAR UV-INDUCED CUTANEOUS INFLAMMATORY RESPONSE IN THE EPIDERM-FT IN VITRO HUMAN SKIN MODEL.

Kandarova, H., Armento, A., Stolper, G., Cooney, C., Li, M., and Hayden, P.J. MatTek Corporation, Ashland, MA, USA. Presented at SOT 2011, Abstract #2574

 

640. SIMULATION OF ELECTRON-BEAM IRRADIATION OF SKIN TISSUE MODEL.

Miller1, J.H., Suleiman1, A., Chrisler2, W.B. and Sowa2, M.B.  1Washington State University Tri-Cities, Richland, Washington 99354; and 2Pacific Northwest National Laboratory, Richland, Washington 99354. Radiation Research, 175, 113–118 (2011).

 

635. Th17 CYTOKINES INTERLEUKIN (IL)-17 AND IL-22 MODULATE DISTINCT INFLAMMATORY AND KERATINOCYTE-RESPONSE PATHWAYS.

Nograles, K.E., Zaba, L.C., Guttman-Yassky, E., Fuentes-Duculan, J., Suarez-Farinas, M., Cardinale, I., Khatcherian, A., Gonzalez,  J., Pierson, K.C., White, T.R., Pensabene, C., Coats, I., Novitskaya, I., Lowes, M.A. and Krueger, J.G.  Laboratory of Investigative Dermatology and Translational Immunomonitoring Resource Center, The Rockefeller University, 1230 York Avenue, New York, NY 10065, U.S.A.  British J. of Dermatol., 159, 1092-1102 (2008).

 

634. UNDERSTANDING METABOLIC PATHWAYS FOR SKIN ANTI-AGING.

Osborne, R., Mullins, L.A., and Jarrold, B.B. P&G Beauty & Grooming, The Procter & Gamble Company, Miami Valley Innovation Center, Cincinnati, Ohio USA. J. of Drugs in Dermatol, 8, 7(Supplement), (2009).

 

630. 3D-WOUND HEALING MODEL: INFLUENCE OF MORPHINE AND SOLID LIPID NANOPARTICLES.

Küchler1, S., Wolf1, N.B., Heilmann1, S., Weindl1, G., Helfmann2, J., Yahya1, M.M., Stein3, C., Schäfer-Korting1, M. 1Institut für Pharmazie, Freie Universität Berlin, Königin-Luise-Str. 2-4, D-14195 Berlin, Germany. 2Laser- und Medizin-Technologie GmbH, Berlin, Germany. 3Klinik für Anaesthesiologie und operative Intensivmedizin, Freie Universität Berlin, Charité – Campus Benjamin Franklin, Germany.  J of Biotechnology, Article in Press, (2010).

 

627. IMPROVED HEALING IN TISSUE CULTURE MODEL OF VESICANT INJURY SHOWN BY HIGH FEATURE ANTIMICROBIAL DRESSING.

Liesenfeld1, B., Mikhaylova1, A., Moore1, D., Toreki1,W., Schultz1,2, G. 1Quick-Med Technologies, 2University of Florida. 2010 Wound Healing Society Conference.

 

623. TAT-MEDIATED DELIVERY OF A DNA REPAIR ENZYME TO SKIN CELLS RAPIDLY INITIATES REPAIR OF UV-INDUCED DNA DAMAGE.

Johnson1, J.L., Lowell1, B.C., Ryabinina1, O.P., Lloyd1,2,3, R.S. and McCullough1,2,3, A.K. 1Center for Research on Occupational and Environmental Toxicology, Oregon Health and Science University, Portland, Oregon, USA. 2The Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, USA and 3Restoration Genetics, Portland, Oregon, USA. J. of Invest. Dermatology, advance online publication, 7 October 2010.

 

621. GENOTOXICITY TESTING USING THE NORMAL HUMAN CELL BASED 3D EPITHELIAL MODELS.

Kaluzhny, Y., Karetsky, V., DeLuca, J., Armento, A., Hayden, P., Ayehunie, S. and Klausner, M. MatTek Corporation, Ashland, MA, USA. IIVS In Vitro Alternatives Forum, October 2010.

 

618. PROTEOMIC ANALYSIS OF LASER MICRODISSECTED MELANOMA CELLS FROM SKIN ORGAN CULTURES.

Hood1,2, B.L., Grahovac3, J., Flint1,2, M.S., Sun1,2,M., Charro2, N., Becker3, D., Wells, A., and Conrads1,3, T.P. 1Departments of Pharmacology & Chemical Biology, University of Pittsburgh. 2Mass Spectrometry Platform, University of Pittsburgh. 3Department of Pathology, University of Pittsburgh. 4Pittsburgh VA HealthCare System. J. of Proteome Research, 9, 3656-3663, 2010.

 

613. EXPRESSION OF PROLIFERATIVE AND INFLAMMATORY MARKERS IN A FULL-THICKNESS HUMAN SKIN EQUIVALENT FOLLOWING EXPOSURE TO THE MODEL SULFUR MUSTARD VESICANT, 2-CHLOROETHYL ETHYL SULFIDE.

Black1, A.T., Hayden2, P.J., Casillas3, R.P., Heck4, D.E., Gerecke1, D.R., Sinko5, P.J., Laskin1, D.L., Laskin6, J.D. 1Pharmacology and Toxicology, Rutgers University, Piscataway, NJ, USA. 2MatTek Corporation, Ashland, MA, USA. 3Battelle Memorial Institute, Columbus, OH, USA. 4Environmental Health Sciences, New York Medical College, Valhalla, NY, USA. 5Pharmaceutics, Rutgers University, Piscataway, NJ, USA. 6Environmental and Occupational Medicine, UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ, USA. Toxicol. Appl. Pharmacol., Article in Press, 2010.

 

612. ASSESSMENT OF PENETRATION OF QUANTUM DOTS THROUGH IN VITRO AND IN VIVO HUMAN SKIN USING THE HUMAN SKIN EQUIVALENT MODEL AND THE TAPE STRIPPING METHOD.

Jeong1, S.H., Kim1, J.H., Lee1, S., Lee2, J.P., Kim2, J.H., Sohn2, K.H., Park2, K.L., Kim3, M-K., Son1, S.W. 1Laboratory of Cell Signaling and Nanomedicine, Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul, South Korea. 2National Institute of Toxicological Research, Seoul, South Korea. 3Department of Biochemistry & Molecular Biology, Korea University College of Medicine, Seoul, South Korea. Biochem. Biophys. Res. Commun., Article in Press, 2010.

 

610. CUTANEOUS WOUND HEALING IN THE EPIDERMFT™ FULL-THICKNESS IN VITRO HUMAN SKIN MODEL: ROLE OF SERUM GROWTH FACTORS.

Armento, A.J., Stolper, G., Cooney, C., Li, M., Klausner, M. and Hayden, P.J. MatTek Corporation, Ashland MA, USA.

 

609. THE SKIN CANCER CHEMOTHERAPEUTIC AGENT INGENOL-3-ANGELATE (PEP005) IS A SUBSTRATE FOR THE EPIDERMAL MULTIDRUG TRANSPORTER (ABCB1) AND TARGETS TUMOR VASCULATURE.

Li1, L., Shukla2, S., Lee1, A., Garfield3, S.H., Maloney4, D.J., Ambudkar2, S.V. and Yuspa1, S.H. 1Laboratory of Cancer Biology and Genetics, 2Laboratory of Cell Biology, and 3Confocal Core Facility, Center for Cancer Research, National Cancer Institute and 4NIH Chemical Genomics Center, National Human Genome Research Institute, NIH, Bethesda, Maryland Cancer Res., 70(11), 4509–19, 2010.

 

608. SULFUR MUSTARD TOXICITY FOLLOWING DERMAL EXPOSURE: ROLE OF OXIDATIVE STRESS, AND ANTIOXIDANT THERAPY.

Paromov1, V., Suntres2, Z., Smith3, M. and Stone1, W.L. 1Department of Pediatrics, East Tennessee State University, Johnson City; 2Northern Ontario School of Medicine, Advanced Technology and Academic Centre, 955 Oliver Road Thunder Bay, ON P7B 5E1; and 3AMAOX, Ltd., #208, 6300 N. Wickham Rd, Melbourne, Fla. J. of Burns and Wounds, 7, 60-85, 2007.

 

604. PROTECTIVE EFFECT OF POMEGRANATE-DERIVED PRODUCTS ON UVB-MEDIATED DAMAGE IN HUMAN RECONSTITUTED SKIN.

Afaq1, F., Zaid1, M.A., Khan1, N., Dreher2, M., and Mukhtar1, H. 1Department of Dermatology, University of Wisconsin, Madison, WI, USA; 2POM Wonderful, Inc., Los Angeles, CA, USA. Experimental Dermatology, 18, 553–561, 2009.

 

599. A NEW DECORIN-LIKE TETRAPEPTIDE FOR OPTIMAL ORGANIZATION OF COLLAGEN FIBRES.

Puig, A., Anton, J.M.G., and Mangues , M. Lipotec SA, Gava, Barcelona, Spain. International J. of Cosmetic Science, 30, 97–104, 2008.

 

596. DC DETOXDEFENSE™ STIMULATES SKIN’S OWN SOD ANTIOXIDANT PROTECTION AND DETOXIFICATION.

Distinctive Cosmetic Ingredients, LLC, South Plainfield, NJ, USA.

 

563. RELATIVE BIOLOGICAL EFFECTIVENESS OF PULSED AND CONTINUOUS 20 MEV PROTONS FOR MICRONUCLEUS INDUCTION IN 3D HUMAN RECONSTRUCTED SKIN TISSUE.

Schmid1, T.E., Dollinger2, G., Hable2, V., Greubel2, C., Zlobinskaya1, O., Michalski1, D., Molls1, M., and Röper1, B, 1Department of Radiation Oncology, Technische Universitaet Muenchen, Germany; 2Institute for Applied Physics and Metrology, Universitaet der Bundeswehr Muenchen, Neubiberg, Germany. Radiother Oncol. 2010 Apr,95 (1): 66–72 Epub 2010 Mar 26.

 

560. EVALUATION OF EPIDERM FULL THICKNESS-300 (EFT-300) AS AN IN VITRO MODEL FOR SKIN IRRITATION: STUDIES ON ALIPHATIC HYDROCARBONS.

Mallampati1, R., Patlolla1, R.R., Agarwal1, S., Babu2, R.J., Hayden3, P., Klausner3, M., Singh1, M.S. 1College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, USA. 2Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA. 3MatTek Corporation, 200 Homer Avenue, Ashland, MA 01721, USA. Toxicology in Vitro, 24, 669-676, (2010).

 

549. AccelaFuze™ PEPTIDE INFUSION THERAPY.

Allan, H., Patterson, M. Woodford Medical Aesthetics, Danbury, Essex, UK.

 

547. Gamma-H2AX AS A BIOMARKER OF DNA DAMAGE INDUCED BY IONIZING RADIATION IN HUMAN PERIPHERAL BLOOD LYMPHOCYTES AND ARTIFICIAL SKIN.

Redon, E., Dickey, J.S., Bonner, W.M., Sedelnikova, O.A. Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, D.H.H.S., Bethesda, MD 20892, USA. J. Adv. Space Res., doi:10.1016//j.asr.2008.10.011 (2008).

 

546. OXIDATIVE STRESS AND INFLAMMATORY RESPONSE IN DERMAL TOXICITY OF SINGLE-WALLED CARBON NANOTUBES.

Murray1,2, A.R., Kisin1, E., Leonard1, S.S., Young1, S.H., Kommineni1, C., Kagan3, V.E., Castranova1,2, V., Shvedova1,2, A.A. 1PPRB/NIOSH, Morgantown, WV, United States. 2Department of Physiology and Pharmacology, WVU, United States. 3Center for Free Radical and Antioxidant Health, Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA, United States. Toxicology, 257, 161-171 (2009).

 

538. EXPRESSION OF STRATUM CORNEUM LIPID PATHWAYS IN HUMAN SKIN EQUIVALENT CULTURES.

Jarrold, B., Mullins, L., Reichling, T., Tiesman, J., Robinson, M., Binder, B., Osborne, R. P&G Beauty, Cincinnati, Ohio USA. Presented at Amer. Acad. of Derm. Meeting, San Antonio (2008).

 

537. ANALYSIS OF IONIZING RADIATION-INDUCED DNA DAMAGE AND REPAIR IN THREE-DIMENSIONAL HUMAN SKIN MODEL SYSTEM.

Su, Y., Meador, J.S., Geard, C.R., and Balajee, A.S. Center for Radiological Research, Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY, USA. Experimental Dermatology, 1600-1625, (2009).

 

535. POMEGRANATE DERIVED PRODUCTS FOR CANCER CHEMOPREVENTION.

Syed, D.N., Afaq, F., Mukhtar, H. University of Wisconsin, Madison, WI, USA. Seminars in Cancer Biology, 17, 377–385 (2007).

 

532. MICROVESICATING EFFECTS OF SULFUR MUSTARD ON AN IN VITRO HUMAN SKIN MODEL.

Hayden1, P.J., Petrali22, J.P., Stolper1, G., Hamilton2, T.A., Jackson Jr1, G.R., Wertz3, P.W., Ito4, S., Smith2, W.J., and Klausner1, M. 1MatTek Corp., 200 Homer Avenue, Ashland, MA 01721, USA. 2US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, USA. 3University of Iowa, Iowa City, IA, USA. 4Harvard Medical School, Boston, MA, USA. Toxicology In Vitro, 23, 1396-1405, (2009).

 

530. SKIN SCIENCE: THE USE OF GENOMICS TOOLS IN SKIN CARE.

Langerveld, A. Genemarkers LLC. Cosmeceuticals Summit, March (2009).

 

527. TO DEVELOP AN IN-VITRO (EFT-300) SKIN MODEL FOR THE STUDY OF WOUND HEALING.

Singh1, M., Mallampati1, R., Patlolla1, R.R., Vashi1, P., Hayden1, P., Klausner1, M. 1College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307. 2MatTek Corporation, 200 Homer Avenue, Ashland, MA 01721. Presented at Society of Toxicology Meeting, Baltimore MD, (2009).

 

526. NFAT REGULATES INDUCTION OF COX-2 AND APOPTOSIS OF KERATINOCYTES IN RESPONSE TO ULTRAVIOLET RADIATION EXPOSURE.

Flockhart1, R.J., Diffey1, B.L., Farr2, P.M., Lloyd3, J., and Reynolds1, N.J. 1Dermatological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK; and 2Department of Dermatology and 3Department of Medical Physics, Royal Victoria Infirmary, Newcastle upon Tyne, UK. FASEB Journal, 22, 4218-4227 (2008).

 

518. IN VITRO SKIN BIOMARKER RESPONSES TO A NEW ANTI-AGING PEPTIDE, PAL-KT.

Osborne1, R., Mullins1, L.A., Jarrold1, B.B., Binder1, R.L., Mondon2, P., Lintner2, K. 1P&G Beauty & Grooming and Global Biotechnology, Cincinnati, Ohio USA. 2Sederma, France.

 

510. TOPICAL N-ACETYL GLUCOSAMINE AND NIACINAMIDE INCREASE HYALURONAN IN VITRO.

Osborne, R., Mullins, L.A., and Robinson, L.R. The Procter & Gamble Company, Cincinnati, Ohio USA.

 

495. RECONSTRUCTED EPIDERMIS AND FULL-THICKNESS SKIN FOR ABSORPTION TESTING: INFLUENCE OF THE VEHICLES USED ON STEROID PERMEATION.

Schäfer-Korting1, M., Mahmoud1, A., Borgia1, S.L., Brüggener1, B., Kleuser1, B., Schreiber1, S., and Mehnert2, W. 1Freie Universität Berlin, Institut für Pharmazie (Pharmakologie & Toxikologie), Berlin, Germany; 2Freie Universität Berlin, Institut für Pharmazie (Pharmazeutische Technologie), Berlin, Germany. ATLA, 36, 441-452, (2008).

 

488. STIMULATION OF EPIDERMAL HYALURONAN BY YEAST FERMENT.

Osborne1, R., Hakozaki2, T., Jarrold1, B., and Mullins1, L. 1Procter & Gamble Beauty, Cincinnati, Ohio, USA and 2Kobe, Japan.

 

486. EVALUATION OF EPIDERM FULL THICKNESS-300 (EFT-300) AS AN IN VITRO MODEL FOR SKIN IRRITATION.

Singh1, M., Mallampati1, R., Hayden2, P., Klausner2, M., Patlolla1, R.R., Babu3, R.J. 1College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307 2MatTek Corporation, 200 Homer Avenue, Ashland, MA 01721 3Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA. Society of Toxicology Annual Meeting, Seattle, WA (2008). The Toxicologist, 102, 1, 68 (2008).

 

485. HEALING OF DERMAL WOUNDS IN THE EPIDERM-FT™ IN VITRO HUMAN SKIN MODEL: AN ANIMAL ALTERNATIVE FOR WOUND HEALING ISSUES.

Hayden, P.J., Stolper, G., Cooney, C., and Klausner, M. MatTek Corporation, Ashland, MA. Society of Toxicology Annual Meeting, Seattle, WA (2008). The Toxicologist, 102, 1, 69 (2008).

 

467. SYNERGISTIC ACTIONS OF PEMPHIGUS VULGARIS IGG, FAS-LIGAND AND TUMOR NECROSIS FACTOR-A DURING INDUCTION OF BASAL CELL SHRINKAGE AND ACANTHOLYSIS.

Orlov, M.D., Chernyavsky, A.I., Arredondo, J. and Grando, S.A. Department of Dermatology, University of California-Davis, Sacramento, CA 95816, USA. Autoimmunity, 39 (7), 557-562, (2006).

 

460. EVALUATION OF COSMETIC INGREDIENTS IN TISSUE ENGINEERED HUMAN SKIN IN VITRO.

Osborne, R., Mullins, L.A., Jarrold, B.B., McPhail, S., Robinson, L. The Procter & Gamble Company, Cincinnati, Ohio USA. Presented at American Association for Advancement of Science Annual Meeting (2007).

 

445. DNA DOUBLE-STRAND BREAKS FORM IN BYSTANDER CELLS AFTER MICROBEAM IRRADIATION OF THREE-DIMENSIONAL HUMAN TISSUE MODELS.

Sedelnikova1, O.A., Nakamura1, A., Kovalchuk2, O., Koturbash2, I., Mitchell3, Marino3, S.A., Brenner3, D.J., and Bonner1, W.M. 1Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland; 2Department of Biological Sciences, University of Lethbridge, Lethbridge, Alberta, Canada; and 3Radiological Research Accelerator Facility, Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, New York. Cancer Res 2007, 67, (9), 4295-302, (2007).

 

422. PHOTOPROTECTIVE EFFECT OF ISOFLAVONE GENISTEIN ON ULTRAVIOLET B-INDUCED PYRIMIDINE DIMER FORMATION AND PCNA EXPRESSION IN HUMAN RECONSTITUTED SKIN AND ITS IMPLICATIONS IN DERMATOLOGY AND PREVENTION OF CUTANEOUS CARCINOGENESIS.

Moore1,3, J., Wang1, Y., Stebbins1, W., Gao1, D., Zhou1, X., Phelps1, R., Lebwohl1, M., Wei,1,2, H. 1Department of Dermatology, 2Department of Oncological Sciences, and 3Department of Radiation Oncology, Mount Sinai School of Medicine, New York, NY. Carcinogenesis, 27, (8), 1627-1635, (2006). ). (Poster presentation with color photos: See TR-373).

 

406. MATRIX METALLOPROTEINASE (MMP) EXPRESSION IN THE EPIDERM-FT SKIN EQUIVALENT: RELEVANCE TO DERMAL WOUND HEALING AND BLISTERING SKIN DISEASES.

Hayden, P.J., Cooney, C., Stolper, G., Klausner, M. MatTek Corporation, Ashland, MA, USA. Presented at the Society for Investigative Dermatology Annual Meeting, Philadelphia, PA, May 3-6 (2006).

 

404. TOPICALLY APPLIED LIPOSOME-ENCAPSULATED T4 ENDONUCLEASE V INCREASES REPAIR OF UV-INDUCED CYCLOBUTANE PYRIMIDINE DIMERS IN NORMAL REPAIR PROFICIENT RECONSTRUCTED SKIN.

Nay¹, S.L., Canning¹, M.T., and Yarosh¹, D.B. ¹AGI Dermatics, Freeport, NY. Poster presented at the Society for Investigative Dermatology Annual Meeting, Philadelphia, PA, May 3-6, (2006).

 

403. EFFECTS IN UNIRRADIATED HUMAN TISSUE INDUCED BY RADIATION DAMAGE UP TO 1 MM AWAY.

Belyakov1,2, O.V., Mitchell1, S.A., Parikh3, D., Randers-Pehrson1, G., Marino1, S.A., Amundson1, S.A., Geard1, C.R. and Brenner1, D.J. 1Center for Radiological Research, Columbia University, New York, NY 10032; 2Radiation Biology Laboratory, Research and Environmental Surveillance, Radiation and Nuclear Safety Authority, P.O. Box 14, FIN-00881, Helsinki, Finland; and 3Stuyvesant High School, New York, NY 10282. Proceedings of the Natl. Acad.of Sci. of the U.S.A, 102, 40, 14203-14208, October (2005).

 

400. NEAR-INFRARED OPTICAL SENSORS BASED ON SINGLE-WALLED CARBON NANOTUBES.

Barone1, PW, Baik1, S, Heller2, DA, Strano1, MS. 1Department of Chemical and Biomolecular Engineering, University of Illinois-Urbana/Champaign, 600 S. Mathews Avenue, Urbana, Illinois 61801, USA; 2Department of Chemistry, University of Illinois-Urbana/Champaign, 505 S. Matthews Avenue, Urbana, Illinois 61801, USA. Nature Materials, 4, 86-92, (2005).

 

396. LONG-TERM BIOLOGICAL BYSTANDER EFFECTS OF MICROBEAM IRRADIATION IN 3D HUMAN TISSUE MODELS.

Sedelnikova1, O.A., Nakamura1, A., Koturbash2, I., Kovalchuk3, O., Mitchell3, S.A., Marino3, S.A., Brenner3, D.J., Bonner1, W.M. 1Laboratory for Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD; 2Department of Biological Sciences, University of Lethbridge, Lethbridge, AB, Canada; 3Radiation Accelerator Research Facility, Center for Radiological Research, Columbia University, College of Physicians and Surgeons, New York, NY. Poster presented at the 7th International Workshop on Microbeam Probes, New York, NY, March 15-17, (2006).

 

389. INFLUENCE OF SOYBEAN SYMBIOSOME EXTRACT ON UV-INDUCED SKIN FREE-RADICAL BIOCHEMISTRY.

James V. Gruber1, Venkat Padyachi1, Lisa Lods1, Michele Benhaim2, Robert Holtz3, Audrey Natalizio4. 1Arch Personal Care Products, South Plainfield, NJ, United States; 2Arch Chemicals, Paris, France; 3BioInnovation Laboratories, Inc., McKinney, TX, United States; 4Dermscan Group, Lyon, France. Presented at 23rd IFSCC Congress, Orlando, FL. October 24-27, (2004).

 

385. USE OF EPIDERM FULL THICKNESS TISSUE FOR ANTI-AGING STUDIES.

Gruber, V., et al. Arch Personal Care Products L.P., South Plainfield, NJ and BioInnovation Laboratories, Inc., McKinney, TX.

 

373. PHOTOPROTECTIVE EFFICACY OF ISOFLAVONE GENISTEIN IN HUMAN RECONSTITUTED SKIN.

Moore, J.O., Gao, D., Wang, Y., Lebwohl, M.G., Wei, H. Mount Sinai School of Medicine, Department of Dermatology, New York, N.Y. Presented at Society of Toxicology 44th Annual Meeting, New Orleans, LA, March 6-10, (2005). (Published paper: See TR-422) Carcinogenesis, 27, 8, 1627-1635 (2006).

 

371. IN VITRO SKIN EQUIVALENT MODELS FOR TOXICITY TESTING.

Hayden, P.J., Ayehunie, S., Jackson, G.R., Kupfer-Lamore, S., Last, T.J., Klausner, M., Kubilus, J. MatTek Corporation, Ashland, MA, U.S.A. Published in Alternative Toxicological Methods. Editors H. Salem, S.A. Katz. CRC Press LLC, Boca Raton, FL, USA, 229-247 (2003).

 

364. DEVELOPMENT OF A FULL THICKNESS IN VITRO HUMAN SKIN EQUIVALENT (EPIDERM-FT) FOR SULFUR MUSTARD RESEARCH.

Hayden1, P.J., Petrali2, J.P., Hamilton2, T.A., Kubilus1, J., Smith2, W.J., Klausner1, M. 1MatTek Corporation, Ashland, MA, USA. 2U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD, USA. Presented at Society of Investigative Dermatology, St.Louis, MO, May 4-7, (2005).

 

362. THE EFFECT OF SCARGUARD ON COLLAGENASE LEVELS USING A FULL-THICKNESS EPIDERMAL MODEL.

Beckenstein1, M.S., Kuniaki1, T., Matarasso2, A. 1Chondrex, Inc., Redmond, WA; 2Albert Einstein School of Medicine, New York, NY. Aesthetic Surg J., 24, (6), 542-546, (2004).

 

339. HUMAN SKIN EQUIVALENT: A RELIABLE IN VITRO MODEL FOR CARCINOGENIC EXPERIMENTS.

Moore, J.O., Stebbins, W.G., Guevara, D., Saladi, R., Zhui, Y., Lebwohl, M.G., Wei, H. Dermatology, Mount Sinai School of Medicine, New York, NY. J. Invest. Dermatol., 122, (3), A23, Abstract #138, (2004).

 

328. WOUND HEALING RESPONSE OF A FULL THICKNESS IN VITRO HUMAN SKIN EQUIVALENT (EPIDERM-FT™ 200) AFTER SOLAR UV-IRRADIATION.

Hayden, P., Burnham, B., Kubilus, J., Klausner, M., and Sheasgreen, J. MatTek Corporation, Ashland, MA. J. Invest. Dermatol., 122, (3), A141, Abstract #842, (2004).

 

327. DETECTING REACTIVE OXYGEN SPECIES IN SKIN USING TWO-PHOTON FLUORESCENCE IMAGING MICROSCOPY.

Hanson1, K., Hayden2, P., Kubilus2, J., Clegg1, R. 1Laboratory for Fluorescence Dynamics, Department of Physics, University of Illinois at Urbana-Champaign. 2MatTek Corp. 200 Homer Avenue, Ashland, MA. J. Invest. Dermatol., 122, (3), A140, Abstract #839, (2004).

 

323. WOUND HEALING RESPONSE OF THE EPIDERM FULL THICKNESS (EPIDERM-FT™) IN VITRO HUMAN SKIN EQUIVALENT AFTER SOLAR UV IRRADIATION: COMPARISON TO EXCISED HUMAN SKIN.

Hayden, P., Burnham,B., Klausner, M., and Kubilus, J. MatTek Corporation, Ashland, MA. Poster Presented at the Society of Toxicology Annual Meeting, Baltimore, MD. March 21-25, (2004). The Toxicologist, 78, S1, 387-388 (2004).

 

300. IN VITRO MODELS OF FULL-THICKNESS HUMAN SKIN (EPIDERMFT™) AND AIRWAY EPITHELIUM (EPIAIRWAYFT™) FOR TOXICOLOGY AND DRUG DEVELOPMENT APPLICATIONS.

P.J. Hayden, M. Klausner, J. Kubilus, B. Burnham and G.R. Jackson. MatTek Corporation, Ashland, MA 01721. Presented at the 2003 Congress on In Vitro Biology, Portland, OR (May 31-June 4).

 

293. EPIDERM™ FULL THICKNESS (EPIDERMFT™), A DERMAL/EPIDERMAL SKIN EQUIVALENT WITH A FULLY DEVELOPED BASEMENT MEMBRANE.

Patrick J. Hayden, Mitch Klausner, Joseph Kubilus, Seyoum Ayehunie, Brenda Burnham, George R. Jackson and John E. Sheasgreen. MatTek Corp., Ashland MA. J. Invest. Dermatol., 121, (1), Abstract #543, (2003).

 

286. EPIDERM™ FULL THICKNESS (EPIDERM-FT™), A DERMAL-EPIDERMAL SKIN MODEL WITH A FULLY DEVELOPED BASEMENT MEMBRANE.

Patrick J. Hayden, Joseph Kubilus, Brenda Burnham, George R. Jackson and Mitch Klausner. MatTek Corp., Ashland, MA (USA). The Toxicologist, 72, S1, 158 (2003).

 

262. FULL THICKNESS EPIDERM™, A DERMAL-EPIDERMAL SKIN MODEL TO STUDY EPITHELIAL-MESENCHYMAL INTERACTIONS.

Kubilus, J., Hayden, P.J., Last, T.J., Ayehunie, S., Bellavance, K.L., Lamore, S.D., Klausner, M. MatTek Corporation, Ashland, MA. ATLA, 32, (1), 75-82, (2004) and J. of Invest. Dermatol., 119, (1), 260, Abstract #316, (2002).

 

 

 

 

 

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