MatTek's patented EpiDerm™ System consists of normal, human-derived epidermal
keratinocytes (NHEK) which have been cultured to form a multilayered, highly
differentiated model of the human epidermis. These "ready-to-use" tissues, also
known generically as Normal Human-3D (NHu-3D), are cultured on specially
prepared cell culture inserts using serum free medium, attain levels of
differentiation on the cutting edge of in vitro skin technology. Ultrastructurally, the
EpiDerm Skin Model closely parallels human skin, thus providing a useful in vitro
means to assess dermal irritancy and toxicology.
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